Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.
Nitroprusside sodium
The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.
Enzalutamide
Use alternative drugs because the use of enzalutamide will decrease the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
Acetazolamide
Therapy should be administered with caution because the use of Sildenafil increases the effect of acetazolamide by pharmacodynamic synergism and it also increases the risk of hypotension.
The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.
Cardiovascular disease:
The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.
Renal dysfunction:
Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.
Liver diseases:
The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.
What are the interactions with phosphodiesterase-5?| interaction with phosphodiesterase-5 |
|---|
| drug-drug interactions |
| drug-food interactions |
| serotonin syndrome |
| use of alcohol |
| use of organic nitrates |
| use of polypharmacy |
| use of within the last four weeks |
| drug-drug interactions of unknown significance |
The Korean Medicine Society (KMRS) is calling for all doctors to stop prescribing Viagra to people suffering from erectile dysfunction (ED).
According to theof the, Viagra is a prescription drug used to treat male impotence, or inability to get and keep an erection hard enough for sex. Erectile dysfunction is a medical condition where men struggle to maintain an erection when they are not sexually stimulated. When a man cannot get or keep an erection hard enough for sexual activity, he or he may be unable to sustain a satisfying sexual experience. Men with ED have a higher risk of getting sexually transmitted diseases like HIV, gonorrhea and syphilis.
Viagra is the medicine for the treatment of erectile dysfunction in men.
Viagra, also known by its generic name sildenafil citrate, is the medication used to treat erectile dysfunction in men. The drug works by increasing blood flow to the penis, making it easier for a man to get and keep an erection. However, it does not increase sexual desire or improve performance, as it does not protect against sexually transmitted infections or diseases.
If you are suffering from erectile dysfunction, you may not be able to have sex without the help of Viagra. Fortunately, there are several other ways that Viagra can help, including:
Some of the most common side effects of Viagra include:
If you are experiencing side effects, you may be prescribed a medicine called a nitrate-based medicine. Nitrate medicines are available over-the-counter and can help manage your condition.
If you are experiencing serious side effects, you may be prescribed an alpha-blocker medicine called a alpha-2-adrenergic blocker. These medicines are available without prescription and can help control your condition.
If you are experiencing side effects from Viagra, you can consult with your doctor. They may suggest you stop taking Viagra and see a doctor immediately.
In addition to Viagra, there are other medicines and lifestyle changes that you can implement to help you stay sexually aroused. They may include:
Viagra usually stays in your system for about 6 to 8 hours after it is taken. Viagra is only available with a doctor’s prescription and is not recommended for everyone. Viagra is not recommended for men with heart disease or high blood pressure. However, some men may be advised to have a vasectomy surgery before having Viagra.
Last updated 14 September 2023
On 14 March 2023, the UK Medicines regulator approved an application to reclassify the erectile dysfunction medication Cialis. When marketed asCialis Together(tadalafil 10mg), it will be a ‘P’ (pharmacy) medication, and so available ‘over the counter’ in pharmacies – see. This follows the 2018, ‘P’ classification of (sildenafil 50mg) which has been available OTC, without a prescription, since then.
This decision is good news for men’s health …. Erectile dysfunction can be a debilitating condition, so it’s important men feel they have fast access to quality and legitimate care
Dr Laura Squire, MHRA’s Chief Officer for Healthcare, Quality and Access
Unfortunately, there is a strong black market in the UK for ED medicines, which are often unlicensed or counterfeit. UK Border Force and the MHRA seize millions of pounds of these fake products from criminals annually. This new classification of tadalafil 10mg will enable men who suffer from ED to obtain it safely from a local pharmacy.
Sanofi, the drug manufacturer, is expected to launch Cialis Together later in 2023. Cialis Together will be available to purchase in pharmacies without a prescription by men over 18 with erectile dysfunction. Cialis Together tablets will contain 10mg tadalafil and the maximum pack size will be 8 tablets. Other doses and pack sizes of Cialis and tadalafil will still be available on prescription through doctors and specially trained pharmacists. Before purchase in a pharmacy there must be an assessment with a pharmacist, who will check that Cialis Together is appropriate and safe, or whether consultation with a GP is necessary.
Men suffering with ED will have another treatment option with the convenience of purchasing it in their local pharmacy, including pharmacies found inside supermarkets (eg. Tesco, Asda, Sainsbury’s). The pharmacist will ask some health questions, may check blood pressure, and will advise on treatment with Cialis Together or Viagra Connect, or the need to consult a GP. Pharmacies usually have a private room for such discussions.
Cialis Together is a 10mg tadalafil product for use at least 30 minutes prior to anticipated sexual activity. Its effects can last. It is not recommended for daily use. The maximum recommended dose of Cialis Together will be one tablet in 24 hours. Prescription Cialis and tadalafil will still be available at different doses.
Dr Fox welcomes the wider access to ED medication for men that Cialis Together classified as a ‘P’ OTC medication will provide. We at Dr Fox are aware of the difficulties men have in discussing ED with their GPs and in accessing ED medication. We know that Cialis is effective and safe for most men and this change provides another option for obtaining ED treatment. Pharmacists are health professionals who are able to give ED advice but they will also know when to refer men who would benefit from a doctor’s assessment. ‘P’ medicines can also be supplied on prescription, and we will offer Cialis Together, when available, alongside our other competitively priced ED products.
Dr Claire Pugh, Dr Fox Medical Director
In the UK have 3 categories:
In the UK a POM is a medicine which is 'over the counter’ in the following ways:
Viagra, the famous pill that has transformed the lives of millions of men, has come under fire for its association with impotence. In a recent report, it was reported that an estimated one in 10 men in India have experienced impotence due to their use of Viagra.
The report also reported a link between Viagra and erectile dysfunction. It was reported that about one in 10 men in India have experienced erectile dysfunction.
It was also stated that one in ten men in India are experiencing impotence, which is an age-related phenomenon. It is estimated that one in 10 men in India are experiencing erectile dysfunction by age 50.
As with any drug, there are some precautions that you should know before taking Viagra.
For men who are suffering from impotence, there are some precautions that you should know to take while using Viagra.
Viagra is a PDE-5 inhibitor that helps relax the blood vessels in the penis. As the blood vessels in your penis become more constricted, you can’t get an erection for the normal amount of time. Therefore, Viagra is effective for treating erectile dysfunction.
For a male to achieve an erection during sex, you should avoid using Viagra, as it can cause a sudden and severe loss of blood flow to your penis.
If you take Viagra or any other medication, you should consult with your doctor to determine if it is the right medication for you.
Men who are suffering from erectile dysfunction may not experience this problem and can only use Viagra as directed.
ViagraShare This Page Add your answer toor other version.=)Shane Williams is a Certified Pharmacist at.
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Answer: You may have questions about buying medication online. We have answered some common questions about buying medication online, and now you can have an online consultation with our pharmacist.Read moreAnswer: You can have a consultation with a qualified healthcare provider from time to time. This is important for customers who live in rural areas or have mobility issues. They can call the company and ask about their medications, including Viagra.
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